Scientific Research Papers
Here are selected research papers on the study of misfolded proteins (or prion particles) and how they affect brain diseases.
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Detection of Misfolded Ab Oligomers for Sensitive Biochemical Diagnosis of Alzheimer’s Disease
Development of a Biochemical Diagnosis of Parkinson Disease by Detection of α-Synuclein Misfolded Aggregates in Cerebrospinal Fluid
De novo induction of amyloid-b deposition in vivo
Brains from non-Alzheimer’s individuals containing amyloid deposits accelerate Aβ deposition in vivo
Prion-like features of misfolded Aβ and tau aggregates
Titration of biologically active amyloid–b seeds in a transgenic mouse model of Alzheimer’s disease
Induction of IAPP amyloid deposition and associated diabetic abnormalities by a prion-like mechanism
Prion-like characteristics of the bacterial protein Microcin E492
Diagnosing prion diseases- needs, challenges and hopes
Amyloids, prions and the inherent infectious nature of misfolded protein aggregates
Protein Misfolding and Neurodegeneration
Generation of prions in vitro and the protein-only hypothesis
Misfolded protein aggregates: Mechanisms, structures and potential for disease transmission
In Vivo Spreading of Tau Pathology
Prion hypothesis: the end of the controversy?
Transmissible Proteins: Expanding the Prion Heresy
Protein Misfolding in Neurodegenerative Diseases: The Key Pending Questions
Amyloid-beta and tau pathology following repetitive mild traumatic brain injury
Type 2 diabetes as a protein misfolding disease
Alpha-Synuclein Oligomers and Neurofilament Light Chain in Spinal Fluid Differentiate Multiple System Atrophy from Lewy Body Synucleinopathies
Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies
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