SYNTapBiomarker Test helps doctors identify underlying synucleinopathy in patient evaluation for Alzheimer’s. Using cerebrospinal fluid (CSF), the test tracks misfolded Synuclein. Studies show up to 40% of Alzheimer’s patients have misfolded Synuclein in their brains, which may affect the course of the disease.


The SYNTap Test revolutionizes LBD diagnosis. This test helps doctors in diagnosing Lewy Body Dementia by tracking the key biomarker, misfolded Synuclein. 

A recently discovered brain disease, LBD has sadly only been diagnostically confirmed through autopsy. This test is a game-changer in LBD diagnosis.


The SYNTap Test helps doctors diagnose Parkinson’s Disease (PD) by identifying misfolded Synuclein, a biomarker associated with the disease.

Doctors have long sought molecular diagnostic tools when they suspect PD. By tracking the biomarker, we help accelerate research to find cures.

Read the FAQ to learn more about our SYNTap Test.

Would you like Amprion to contact a doctor for testing availability? 

REFER A doctor

* A physician must prescribe the SYNTap™ Biomarker Test. If you would like us to reach out to your doctor, please complete this form.*

Currently, Amprion offers this test on a self-pay basis. We provide financial assistance programs for those who are eligible. In addition, we’re working hard to establish reimbursement from insurance providers, Medicare, and Medicaid. This test is presently available throughout the US, except Maryland, New York, and Rhode Island.

I’d like Amprion to Contact My Doctor

Please send information about Amprion and the
SYNTap Biomarker Test to my physician:

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SYNTap™ Biomarker Test
Frequently Asked Questions

The SYNTap Biomarker Test is a breakthrough test exclusively offered by Amprion. It is not currently covered by private insurance, Medicare, or Medicaid. At present, Amprion does not submit claims to insurance companies. Therefore, patients are responsible for the cost of the test.

During this early release of the SYNTap Test, we are only accepting direct-bill or self-pay patients. For this period, the cost of the test is $1,500.

Medicare does not currently cover the SYNTap Biomarker Test. Medicare patients must complete the Advance Beneficiary Notice (ABN) acknowledging that you are responsible for the cost of the test. The ABN must be signed and sumbited prior to the test being performed.  

The test is currently available throughout the US, except Maryland, Rhode Island, and New York. We are working hard to ensure the SYNTap Test is available in all states as soon as possible.

Amprion accepts credit cards, personal checks, and money orders. Patients can make a payment via mail or over the phone. For additional details or questions, please contact: 

Patient Billing Center:
Telephone: 1-858-461-6338 (M-F 9AM – 5PM PST)

Yes, we offer payment plans and financial assistance. For details, please get in touch with our billing department.

Patient Billing Center:
Telephone: 1-858-461-6338 (M-F 9AM – 5PM PST)

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